PhD Student (Exceptional Postdoctoral Candidates Will Also Be Considered) – Structural Mass Spectrometry of Oligonucleotides and Their Therapeutic Applications

Doctorat / PhD Profil chercheur : First Stage Researcher (R1) Recognised Researcher (R2) Type de contrat : Temporary Date limite de candidature : 15 Nov 2026 - 12:00 (Europe/Brussels) Date de début : 1 Mar 2027 Programme UE : Not funded by a EU programme Département : Pharmaceutical Sciences Domaine : Physics » Biophysics

The Biophysical and Bioanalytical Mass Spectrometry Laboratory at the University of Geneva develops and applies mass spectrometry methods to study the structure, folding, and chemical modifications of nucleic acids. We seek a PhD candidate to develop advanced mass spectrometry methods for the structural characterization of oligonucleotides, including higher-order structures, folding, and fragmentation pathways. Particular emphasis will be placed on therapeutically relevant oligonucleotides, although more fundamental questions related to nucleic acid structure and biophysics may also be addressed. The project combines native mass spectrometry, ion mobility spectrometry, and advanced fragmentation methods. Exceptional postdoctoral candidates will also be considered. Outstanding applicants may alternatively propose their own research project aligned with the laboratory interests through the Wild Card option (see form).

Where to apply E-mail [email]